Drug interactions
Ethinyl estradiol-norgestimate + Oteseconazole
Severity: Minor
Ethinyl estradiol-norgestimate and Oteseconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oteseconazole inhibits BCRP and may raise ethinyl estradiol exposure. Oteseconazole is only used in women who cannot become pregnant, so concurrent use in contraceptive users is unusual.
What this interaction means in plain words
Ethinyl estradiol-norgestimate and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethinyl estradiol-norgestimate belongs to Endocrine; Oteseconazole belongs to Anti Fungals.
Why it happens
BCRP inhibition by oteseconazole increases ethinyl estradiol exposure.
What to do
Monitor for estrogenic adverse effects if coadministered. Reconsider oteseconazole use in women of reproductive potential since it is contraindicated for them.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ethinyl estradiol-norgestimate
- Ethinyl estradiol-norgestimate + Fezolinetant Contraindicated
- Ethinyl estradiol-norgestimate + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-norgestimate + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-norgestimate Major
- Amobarbital + Ethinyl estradiol-norgestimate Major
- Anastrozole + Ethinyl estradiol-norgestimate Major
Other interactions of Oteseconazole
- Atorvastatin + Oteseconazole Moderate
- Fluvastatin + Oteseconazole Moderate
- Glibenclamide + Oteseconazole Moderate
- Glyburide-metformin + Oteseconazole Moderate
- Irinotecan + Oteseconazole Moderate
- Lapatinib + Oteseconazole Moderate
Frequently asked questions
Can I take Ethinyl estradiol-norgestimate with Oteseconazole?
MediHelp rates the interaction as minor. Ethinyl estradiol-norgestimate and Oteseconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oteseconazole inhibits BCRP and may raise ethinyl estradiol exposure. Oteseconazole is only used in women who cannot become pregnant, so concurrent use in contraceptive users is unusual.
How serious is the interaction between Ethinyl estradiol-norgestimate and Oteseconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for estrogenic adverse effects if coadministered. Reconsider oteseconazole use in women of reproductive potential since it is contraindicated for them.
What other medicines interact with Ethinyl estradiol-norgestimate?
MediHelp also lists interactions of Ethinyl estradiol-norgestimate with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-norgestimate page.
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