Drug interactions
Etomidate + Timolol
Severity: Minor
Etomidate and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etomidate generally has little hemodynamic effect, but induction in a patient on a beta-blocker can still lead to hypotension and blunted heart rate responses. Systemic effects of timolol, including from eye drops, may contribute during anesthesia.
What this interaction means in plain words
Etomidate and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etomidate belongs to Central Nervous System; Timolol belongs to Cardiovascular.
Why it happens
Additive hemodynamic depression and blunted compensatory sympathetic response from beta-blockade.
What to do
Monitor blood pressure and heart rate during induction and treat hypotension promptly. Continue beta-blocker therapy perioperatively unless otherwise indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Etomidate
- Alprazolam + Etomidate Moderate
- Amitriptyline + Etomidate Moderate
- Amobarbital + Etomidate Moderate
- Azelastine + Etomidate Moderate
- Baclofen + Etomidate Moderate
- Brompheniramine + Etomidate Moderate
Frequently asked questions
Can I take Etomidate with Timolol?
MediHelp rates the interaction as minor. Etomidate and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etomidate generally has little hemodynamic effect, but induction in a patient on a beta-blocker can still lead to hypotension and blunted heart rate responses. Systemic effects of timolol, including from eye drops, may contribute during anesthesia.
How serious is the interaction between Etomidate and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during induction and treat hypotension promptly. Continue beta-blocker therapy perioperatively unless otherwise indicated.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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