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Drug interactions

Etonogestrel + Insulin degludec-liraglutide

Severity: Minor

Etonogestrel and Insulin degludec-liraglutide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Progestins may slightly impair glucose tolerance and so oppose the effect of antidiabetic therapy. The effect of etonogestrel alone is usually small, but glycemic control may shift in some patients with diabetes.

What this interaction means in plain words

Etonogestrel and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Etonogestrel belongs to Endocrine; Insulin degludec-liraglutide belongs to Endocrine.

Evidence level: Low

Why it happens

Pharmacodynamic antagonism through progestin-related reduction in glucose tolerance.

What to do

Check glucose control more often after etonogestrel is started or removed. Adjust the insulin dose if readings drift.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Etonogestrel with Insulin degludec-liraglutide?

MediHelp rates the interaction as minor. Etonogestrel and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Progestins may slightly impair glucose tolerance and so oppose the effect of antidiabetic therapy. The effect of etonogestrel alone is usually small, but glycemic control may shift in some patients with diabetes.

How serious is the interaction between Etonogestrel and Insulin degludec-liraglutide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check glucose control more often after etonogestrel is started or removed. Adjust the insulin dose if readings drift.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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