Drug interactions
Etonogestrel + Insulin degludec
Severity: Minor
Etonogestrel and Insulin degludec: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Progestins such as etonogestrel may slightly impair glucose tolerance and diminish insulin effect, but the effect with the implant is generally small.
What this interaction means in plain words
Etonogestrel and Insulin degludec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etonogestrel belongs to Endocrine; Insulin degludec belongs to Endocrine.
Why it happens
Progestins may cause mild peripheral insulin resistance, opposing insulin action.
What to do
Monitor blood glucose after starting or removing etonogestrel and adjust the insulin dose only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec
Other interactions of Etonogestrel
Frequently asked questions
Can I take Etonogestrel with Insulin degludec?
MediHelp rates the interaction as minor. Etonogestrel and Insulin degludec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Progestins such as etonogestrel may slightly impair glucose tolerance and diminish insulin effect, but the effect with the implant is generally small.
How serious is the interaction between Etonogestrel and Insulin degludec?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or removing etonogestrel and adjust the insulin dose only if control changes.
What other medicines interact with Insulin degludec?
MediHelp also lists interactions of Insulin degludec with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin degludec page.
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