Drug interactions
Etoposide + Finerenone
Severity: Minor
Etoposide and Finerenone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etoposide may weakly inhibit CYP3A4 and slightly raise finerenone levels. This could increase the risk of hyperkalemia, especially in patients with kidney impairment.
What this interaction means in plain words
Etoposide and Finerenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etoposide belongs to Oncology; Finerenone belongs to Cardiovascular.
Why it happens
Weak CYP3A4 inhibition may reduce finerenone metabolism; the effect of etoposide is not well established.
What to do
Monitor serum potassium and renal function during concurrent use, and adjust finerenone if potassium rises.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etoposide
- Adenovirus types 4 and 7 live + Etoposide Contraindicated
- Etoposide + Pentostatin Contraindicated
- Cyclosporin + Etoposide Major
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Etoposide Major
- Etoposide + Fingolimod Major
- Etoposide + Fosphenytoin Major
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Etoposide with Finerenone?
MediHelp rates the interaction as minor. Etoposide and Finerenone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etoposide may weakly inhibit CYP3A4 and slightly raise finerenone levels. This could increase the risk of hyperkalemia, especially in patients with kidney impairment.
How serious is the interaction between Etoposide and Finerenone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function during concurrent use, and adjust finerenone if potassium rises.
What other medicines interact with Etoposide?
MediHelp also lists interactions of Etoposide with, for example, Adenovirus types 4 and 7 live, Pentostatin, Cyclosporin. The full list is on the Etoposide page.
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