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Drug interactions

Etravirine + Fesoterodine

Severity: Minor

Etravirine and Fesoterodine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Etravirine is a CYP3A4 inducer and may lower exposure to the active metabolite of fesoterodine. This could reduce control of overactive bladder symptoms, though the effect is likely modest.

What this interaction means in plain words

Etravirine and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Etravirine belongs to Anti Virals; Fesoterodine belongs to Genitourinary.

Evidence level: Low

Why it happens

Induction of CYP3A4 increases clearance of the active metabolite of fesoterodine.

What to do

Monitor urinary symptom control and adjust the fesoterodine dose within the labeled range if the response is inadequate.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Etravirine with Fesoterodine?

MediHelp rates the interaction as minor. Etravirine and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etravirine is a CYP3A4 inducer and may lower exposure to the active metabolite of fesoterodine. This could reduce control of overactive bladder symptoms, though the effect is likely modest.

How serious is the interaction between Etravirine and Fesoterodine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor urinary symptom control and adjust the fesoterodine dose within the labeled range if the response is inadequate.

What other medicines interact with Fesoterodine?

MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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