Drug interactions
Etravirine + Oxybutynin
Severity: Minor
Etravirine and Oxybutynin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etravirine induces CYP3A4 and may lower oxybutynin concentrations, potentially reducing efficacy for overactive bladder. The magnitude is not well characterized.
What this interaction means in plain words
Etravirine and Oxybutynin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etravirine belongs to Anti Virals; Oxybutynin belongs to Genitourinary.
Why it happens
CYP3A4 induction by etravirine increases oxybutynin metabolism.
What to do
Monitor bladder symptoms and increase the oxybutynin dose if response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxybutynin
Other interactions of Etravirine
- Efavirenz + Etravirine Contraindicated
- Etravirine + Isavuconazole Contraindicated
- Amobarbital + Etravirine Major
- Apalutamide + Etravirine Major
- Carbamazepine + Etravirine Major
- Cobicistat + Etravirine Major
Frequently asked questions
Can I take Etravirine with Oxybutynin?
MediHelp rates the interaction as minor. Etravirine and Oxybutynin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etravirine induces CYP3A4 and may lower oxybutynin concentrations, potentially reducing efficacy for overactive bladder. The magnitude is not well characterized.
How serious is the interaction between Etravirine and Oxybutynin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor bladder symptoms and increase the oxybutynin dose if response is inadequate.
What other medicines interact with Oxybutynin?
MediHelp also lists interactions of Oxybutynin with, for example, Bethanechol, Clozapine, Potassium chloride. The full list is on the Oxybutynin page.
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