Drug interactions
Everolimus + Influenza virus vaccine quadrivalent cell-cultured
Severity: Minor
Everolimus and Influenza virus vaccine quadrivalent cell-cultured: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus may reduce the immune response to cell-cultured inactivated influenza vaccine. There is no replication risk, but protection may be less than in non-immunosuppressed patients.
What this interaction means in plain words
Everolimus and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
mTOR inhibition dampens lymphocyte proliferation and vaccine-induced antibody production.
What to do
Vaccinate annually as recommended without stopping everolimus. Reinforce other preventive measures during influenza season.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Everolimus with Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates the interaction as minor. Everolimus and Influenza virus vaccine quadrivalent cell-cultured have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Everolimus may reduce the immune response to cell-cultured inactivated influenza vaccine. There is no replication risk, but protection may be less than in non-immunosuppressed patients.
How serious is the interaction between Everolimus and Influenza virus vaccine quadrivalent cell-cultured?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate annually as recommended without stopping everolimus. Reinforce other preventive measures during influenza season.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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