Drug interactions
Everolimus + Lonapegsomatropin
Severity: Minor
Everolimus and Lonapegsomatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase CYP450-mediated clearance, which could lower everolimus concentrations. The evidence is limited and the clinical effect is uncertain.
What this interaction means in plain words
Everolimus and Lonapegsomatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Everolimus belongs to Oncology; Lonapegsomatropin belongs to Endocrine.
Why it happens
Growth hormone may induce CYP3A4 activity, though this is not firmly established.
What to do
Monitor everolimus trough levels and clinical response when lonapegsomatropin is started or stopped, and adjust the dose if levels fall.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Other interactions of Lonapegsomatropin
Frequently asked questions
Can I take Everolimus with Lonapegsomatropin?
MediHelp rates the interaction as minor. Everolimus and Lonapegsomatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase CYP450-mediated clearance, which could lower everolimus concentrations. The evidence is limited and the clinical effect is uncertain.
How serious is the interaction between Everolimus and Lonapegsomatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor everolimus trough levels and clinical response when lonapegsomatropin is started or stopped, and adjust the dose if levels fall.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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