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Drug interactions

Everolimus + Maitake

Severity: Minor

Everolimus and Maitake: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maitake mushroom has reported immune-stimulating properties that could in theory oppose everolimus immunosuppression. Clinical data are lacking, so the effect is uncertain.

What this interaction means in plain words

Everolimus and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic opposition from immunostimulant beta-glucans; not clearly established.

What to do

Advise patients on everolimus, particularly transplant recipients, to avoid maitake supplements. If used, monitor for rejection or loss of efficacy.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Everolimus with Maitake?

MediHelp rates the interaction as minor. Everolimus and Maitake have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maitake mushroom has reported immune-stimulating properties that could in theory oppose everolimus immunosuppression. Clinical data are lacking, so the effect is uncertain.

How serious is the interaction between Everolimus and Maitake?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients on everolimus, particularly transplant recipients, to avoid maitake supplements. If used, monitor for rejection or loss of efficacy.

What other medicines interact with Everolimus?

MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.

Full monographs, dosing and an interaction checker in the MediHelp app

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