Drug interactions
Everolimus + Meningococcal a c y and w-135 polysaccharide vaccine combined
Severity: Moderate
Everolimus and Meningococcal a c y and w-135 polysaccharide vaccine combined: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This is a non-live vaccine, so infection risk is not the concern; everolimus may reduce the antibody response and leave patients less protected.
What this interaction means in plain words
Everolimus and Meningococcal a c y and w-135 polysaccharide vaccine combined can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
mTOR inhibition reduces lymphocyte proliferation and vaccine-induced antibody production.
What to do
Vaccinate before everolimus where possible and give recommended boosters. Consider checking antibody response in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Everolimus with Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates the interaction as moderate. Everolimus and Meningococcal a c y and w-135 polysaccharide vaccine combined can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. This is a non-live vaccine, so infection risk is not the concern; everolimus may reduce the antibody response and leave patients less protected.
How serious is the interaction between Everolimus and Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before everolimus where possible and give recommended boosters. Consider checking antibody response in high-risk patients.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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