Drug interactions
Everolimus + Quercetin
Severity: Minor
Everolimus and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin is a dietary flavonoid supplement with variable effects on drug transporters and enzymes, and its effect on everolimus is not well characterized. Any change in everolimus exposure is uncertain.
What this interaction means in plain words
Everolimus and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Quercetin may modulate P-glycoprotein and CYP3A4 activity, but the direction and magnitude of effect on everolimus are not established.
What to do
Advise patients to avoid high-dose quercetin supplements. If they are used, monitor everolimus trough levels.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Everolimus with Quercetin?
MediHelp rates the interaction as minor. Everolimus and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin is a dietary flavonoid supplement with variable effects on drug transporters and enzymes, and its effect on everolimus is not well characterized. Any change in everolimus exposure is uncertain.
How serious is the interaction between Everolimus and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid high-dose quercetin supplements. If they are used, monitor everolimus trough levels.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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