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Drug interactions

Everolimus + Tick-borne encephalitis vaccine

Severity: Minor

Everolimus and Tick-borne encephalitis vaccine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Inactivated tick-borne encephalitis vaccine cannot cause infection, but everolimus may weaken the immune response. This may leave patients incompletely protected.

What this interaction means in plain words

Everolimus and Tick-borne encephalitis vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

mTOR-mediated immunosuppression may reduce vaccine antibody response.

What to do

Give the vaccine if indicated, ideally before starting everolimus. Consider serologic testing after the series in patients at ongoing exposure risk.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Everolimus with Tick-borne encephalitis vaccine?

MediHelp rates the interaction as minor. Everolimus and Tick-borne encephalitis vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inactivated tick-borne encephalitis vaccine cannot cause infection, but everolimus may weaken the immune response. This may leave patients incompletely protected.

How serious is the interaction between Everolimus and Tick-borne encephalitis vaccine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine if indicated, ideally before starting everolimus. Consider serologic testing after the series in patients at ongoing exposure risk.

What other medicines interact with Everolimus?

MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.

Full monographs, dosing and an interaction checker in the MediHelp app

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