Drug interactions
Everolimus + Turmeric
Severity: Minor
Everolimus and Turmeric: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Curcumin in turmeric has shown inhibition of CYP3A4 and P-glycoprotein in laboratory studies, which might raise everolimus levels. Clinical evidence is limited and the effect from dietary amounts is likely small.
What this interaction means in plain words
Everolimus and Turmeric have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Curcumin may inhibit intestinal CYP3A4 and P-glycoprotein, though this is largely theoretical.
What to do
Advise patients to avoid high-dose turmeric or curcumin supplements. If they are used, monitor everolimus trough levels.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Everolimus and Turmeric, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Everolimus with Turmeric?
MediHelp rates the interaction as minor. Everolimus and Turmeric have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Curcumin in turmeric has shown inhibition of CYP3A4 and P-glycoprotein in laboratory studies, which might raise everolimus levels. Clinical evidence is limited and the effect from dietary amounts is likely small.
How serious is the interaction between Everolimus and Turmeric?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid high-dose turmeric or curcumin supplements. If they are used, monitor everolimus trough levels.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
