Drug interactions
Felodipine + Nadolol
Severity: Moderate
Felodipine and Nadolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining a dihydropyridine calcium channel blocker with a beta-blocker lowers blood pressure further and is often used deliberately. Excessive hypotension, bradycardia, or reflex tachycardia suppression may occur. Heart failure can worsen in vulnerable patients.
What this interaction means in plain words
Felodipine and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Felodipine belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from vasodilation (felodipine) and beta-blockade (nadolol).
What to do
Monitor blood pressure and heart rate, especially when starting or changing doses. Reduce the dose of either drug if symptomatic hypotension or bradycardia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Frequently asked questions
Can I take Felodipine with Nadolol?
MediHelp rates the interaction as moderate. Felodipine and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining a dihydropyridine calcium channel blocker with a beta-blocker lowers blood pressure further and is often used deliberately. Excessive hypotension, bradycardia, or reflex tachycardia suppression may occur. Heart failure can worsen in vulnerable patients.
How serious is the interaction between Felodipine and Nadolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, especially when starting or changing doses. Reduce the dose of either drug if symptomatic hypotension or bradycardia develops.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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