Drug interactions
Felodipine + Saxagliptin-metformin
Severity: Minor
Felodipine and Saxagliptin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dihydropyridine calcium channel blockers may slightly raise blood glucose in some patients, but the effect is generally small. Clinically significant loss of control is uncommon.
What this interaction means in plain words
Felodipine and Saxagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Saxagliptin-metformin belongs to Endocrine.
Why it happens
Calcium channel blockade may modestly reduce insulin release; the mechanism is not firmly established.
What to do
No routine change is needed; check glucose when felodipine is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin-metformin
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Saxagliptin-metformin?
MediHelp rates the interaction as minor. Felodipine and Saxagliptin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dihydropyridine calcium channel blockers may slightly raise blood glucose in some patients, but the effect is generally small. Clinically significant loss of control is uncommon.
How serious is the interaction between Felodipine and Saxagliptin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check glucose when felodipine is started or stopped.
What other medicines interact with Saxagliptin-metformin?
MediHelp also lists interactions of Saxagliptin-metformin with, for example, Atazanavir, Clozapine, Contrast media. The full list is on the Saxagliptin-metformin page.
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