Drug interactions
Felodipine + Vecuronium
Severity: Minor
Felodipine and Vecuronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may modestly enhance and prolong the neuromuscular blockade produced by non-depolarising agents such as vecuronium. The effect is usually small but can lengthen recovery time after surgery.
What this interaction means in plain words
Felodipine and Vecuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Vecuronium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade reduces presynaptic calcium-dependent acetylcholine release, adding to postsynaptic nicotinic receptor blockade.
What to do
Monitor neuromuscular function with train-of-four during anaesthesia and titrate vecuronium to effect; expect possibly slower recovery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Felodipine and Vecuronium, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Vecuronium
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Vecuronium?
MediHelp rates the interaction as minor. Felodipine and Vecuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may modestly enhance and prolong the neuromuscular blockade produced by non-depolarising agents such as vecuronium. The effect is usually small but can lengthen recovery time after surgery.
How serious is the interaction between Felodipine and Vecuronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with train-of-four during anaesthesia and titrate vecuronium to effect; expect possibly slower recovery.
What other medicines interact with Vecuronium?
MediHelp also lists interactions of Vecuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Vecuronium page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
