Drug interactions
Fenfluramine + Formoterol
Severity: Moderate
Fenfluramine and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have sympathomimetic activity. Combined use may increase heart rate and blood pressure and cause palpitations or arrhythmias, particularly in patients with cardiovascular disease.
What this interaction means in plain words
Fenfluramine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fenfluramine belongs to Central Nervous System; Formoterol belongs to Respiratory.
Why it happens
Additive adrenergic stimulation via direct beta-agonism and serotonergic or indirect sympathomimetic effects.
What to do
Monitor blood pressure and heart rate, and avoid the combination in patients with significant cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Fenfluramine
- Fenfluramine + Isocarboxazid Contraindicated
- Fenfluramine + Linezolid Contraindicated
- Fenfluramine + Phenelzine Contraindicated
- Fenfluramine + Selegiline Contraindicated
- Fenfluramine + Tranylcypromine Contraindicated
- Almotriptan + Fenfluramine Major
Frequently asked questions
Can I take Fenfluramine with Formoterol?
MediHelp rates the interaction as moderate. Fenfluramine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sympathomimetic activity. Combined use may increase heart rate and blood pressure and cause palpitations or arrhythmias, particularly in patients with cardiovascular disease.
How serious is the interaction between Fenfluramine and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and avoid the combination in patients with significant cardiovascular disease.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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