Drug interactions
Fenfluramine + Levosalbutamol
Severity: Moderate
Fenfluramine and Levosalbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenfluramine has serotonergic and some sympathomimetic activity and can raise blood pressure and heart rate, while levosalbutamol can cause tachycardia and palpitations. Combined use may add to cardiovascular stimulation, which matters in patients with heart disease or pulmonary hypertension.
What this interaction means in plain words
Fenfluramine and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fenfluramine belongs to Central Nervous System; Levosalbutamol belongs to Respiratory.
Why it happens
Additive sympathomimetic and cardiovascular stimulation via different pathways.
What to do
Monitor heart rate and blood pressure when levosalbutamol is used regularly with fenfluramine. Reassess the need for frequent beta-agonist doses if palpitations or tachycardia occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Fenfluramine
- Fenfluramine + Isocarboxazid Contraindicated
- Fenfluramine + Linezolid Contraindicated
- Fenfluramine + Phenelzine Contraindicated
- Fenfluramine + Selegiline Contraindicated
- Fenfluramine + Tranylcypromine Contraindicated
- Almotriptan + Fenfluramine Major
Frequently asked questions
Can I take Fenfluramine with Levosalbutamol?
MediHelp rates the interaction as moderate. Fenfluramine and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenfluramine has serotonergic and some sympathomimetic activity and can raise blood pressure and heart rate, while levosalbutamol can cause tachycardia and palpitations. Combined use may add to cardiovascular stimulation, which matters in patients with heart disease or pulmonary hypertension.
How serious is the interaction between Fenfluramine and Levosalbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when levosalbutamol is used regularly with fenfluramine. Reassess the need for frequent beta-agonist doses if palpitations or tachycardia occur.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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