Drug interactions
Fenoldopam + Sotalol
Severity: Moderate
Fenoldopam and Sotalol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenoldopam is a short-acting intravenous vasodilator, and sotalol also lowers blood pressure and heart rate. Together they may produce additive hypotension, and beta-blockade may blunt the reflex tachycardia that fenoldopam normally causes.
What this interaction means in plain words
Fenoldopam and Sotalol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotensive effects via dopamine-1 vasodilation and beta-blockade.
What to do
Monitor blood pressure and heart rate continuously during fenoldopam infusion and titrate the dose to response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Frequently asked questions
Can I take Fenoldopam with Sotalol?
MediHelp rates the interaction as moderate. Fenoldopam and Sotalol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenoldopam is a short-acting intravenous vasodilator, and sotalol also lowers blood pressure and heart rate. Together they may produce additive hypotension, and beta-blockade may blunt the reflex tachycardia that fenoldopam normally causes.
How serious is the interaction between Fenoldopam and Sotalol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate continuously during fenoldopam infusion and titrate the dose to response.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
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