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Drug interactions

Fenoprofen + Nitazoxanide

Severity: Minor

Fenoprofen and Nitazoxanide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Nitazoxanide's active metabolite tizoxanide is highly protein bound and could theoretically displace other highly bound drugs such as fenoprofen. Clinically meaningful effects have not been well documented.

What this interaction means in plain words

Fenoprofen and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Fenoprofen belongs to Musculoskeletal; Nitazoxanide belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Theoretical competition for plasma protein binding sites.

What to do

No specific action is needed. Be aware of increased NSAID adverse effects if symptoms appear during a short course of nitazoxanide.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fenoprofen with Nitazoxanide?

MediHelp rates the interaction as minor. Fenoprofen and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nitazoxanide's active metabolite tizoxanide is highly protein bound and could theoretically displace other highly bound drugs such as fenoprofen. Clinically meaningful effects have not been well documented.

How serious is the interaction between Fenoprofen and Nitazoxanide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Be aware of increased NSAID adverse effects if symptoms appear during a short course of nitazoxanide.

What other medicines interact with Fenoprofen?

MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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