Drug interactions
Fenoprofen + Travoprost
Severity: Minor
Fenoprofen and Travoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reports on NSAIDs and ophthalmic prostaglandin analogues show inconsistent effects on intraocular pressure, with some suggesting reduced travoprost efficacy. A clinically significant systemic interaction is not expected.
What this interaction means in plain words
Fenoprofen and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenoprofen belongs to Musculoskeletal; Travoprost belongs to Miscellaneous.
Why it happens
NSAID inhibition of prostaglandin synthesis may alter the prostaglandin-mediated uveoscleral outflow response; the mechanism is not well established.
What to do
Monitor intraocular pressure if fenoprofen is started or stopped in a patient on travoprost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Diclofenac + Travoprost Minor
Frequently asked questions
Can I take Fenoprofen with Travoprost?
MediHelp rates the interaction as minor. Fenoprofen and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reports on NSAIDs and ophthalmic prostaglandin analogues show inconsistent effects on intraocular pressure, with some suggesting reduced travoprost efficacy. A clinically significant systemic interaction is not expected.
How serious is the interaction between Fenoprofen and Travoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor intraocular pressure if fenoprofen is started or stopped in a patient on travoprost.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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