Drug interactions
Ferric maltol + Rabeprazole
Severity: Minor
Ferric maltol and Rabeprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rabeprazole raises gastric pH, which may reduce the dissolution and absorption of oral ferric maltol. Iron uptake may be lower and the response to iron replacement may be blunted.
What this interaction means in plain words
Ferric maltol and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ferric maltol belongs to Miscellaneous; Rabeprazole belongs to Gastrointestinal Tract.
Why it happens
Reduced gastric acidity impairs dissolution and absorption of oral iron.
What to do
Monitor hemoglobin and ferritin response to ferric maltol during long-term PPI therapy. Consider whether the PPI is still needed if iron response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rabeprazole
- Rabeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Rabeprazole Major
- Atazanavir + Rabeprazole Major
- Dacomitinib + Rabeprazole Major
- Dasatinib + Rabeprazole Major
- Erlotinib + Rabeprazole Major
Other interactions of Ferric maltol
- Aluminum hydroxide + Ferric maltol Moderate
- Calcium carbonate + Ferric maltol Moderate
- Calcium + Ferric maltol Moderate
- Carbidopa-entacapone-levodopa + Ferric maltol Moderate
- Carbidopa-levodopa + Ferric maltol Moderate
- Cimetidine + Ferric maltol Moderate
Frequently asked questions
Can I take Ferric maltol with Rabeprazole?
MediHelp rates the interaction as minor. Ferric maltol and Rabeprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rabeprazole raises gastric pH, which may reduce the dissolution and absorption of oral ferric maltol. Iron uptake may be lower and the response to iron replacement may be blunted.
How serious is the interaction between Ferric maltol and Rabeprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin response to ferric maltol during long-term PPI therapy. Consider whether the PPI is still needed if iron response is inadequate.
What other medicines interact with Rabeprazole?
MediHelp also lists interactions of Rabeprazole with, for example, Rilpivirine, Acalabrutinib, Atazanavir. The full list is on the Rabeprazole page.
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