Drug interactions
Ferrous gluconate + Omadacycline
Severity: Moderate
Ferrous gluconate and Omadacycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron binds oral omadacycline in the gut and reduces its absorption, which may lower antibacterial effect.
What this interaction means in plain words
Ferrous gluconate and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous gluconate belongs to Miscellaneous; Omadacycline belongs to Anti Bacterial.
Why it happens
Iron cations chelate the tetracycline in the gastrointestinal tract, decreasing absorption.
What to do
Take omadacycline at least 4 hours before or after iron-containing products. Observe omadacycline's fasting requirements.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous gluconate
Other interactions of Omadacycline
- Acitretin + Omadacycline Contraindicated
- Isotretinoin + Omadacycline Major
- Omadacycline + Tretinoin Major
- Aluminum hydroxide + Omadacycline Moderate
- Amoxicillin-clavulanic acid + Omadacycline Moderate
- Amoxicillin + Omadacycline Moderate
Frequently asked questions
Can I take Ferrous gluconate with Omadacycline?
MediHelp rates the interaction as moderate. Ferrous gluconate and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds oral omadacycline in the gut and reduces its absorption, which may lower antibacterial effect.
How serious is the interaction between Ferrous gluconate and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take omadacycline at least 4 hours before or after iron-containing products. Observe omadacycline's fasting requirements.
What other medicines interact with Ferrous gluconate?
MediHelp also lists interactions of Ferrous gluconate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous gluconate page.
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