Drug interactions
Fesoterodine + Fluvoxamine
Severity: Minor
Fesoterodine and Fluvoxamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluvoxamine inhibits CYP2D6 weakly and CYP3A4 modestly, and may increase exposure to the active metabolite of fesoterodine. The expected change is small.
What this interaction means in plain words
Fesoterodine and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Fluvoxamine belongs to Central Nervous System.
Why it happens
Fluvoxamine inhibits CYP3A4 and CYP2D6, reducing clearance of the active fesoterodine metabolite.
What to do
No routine adjustment; monitor for anticholinergic adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fesoterodine
Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Frequently asked questions
Can I take Fesoterodine with Fluvoxamine?
MediHelp rates the interaction as minor. Fesoterodine and Fluvoxamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluvoxamine inhibits CYP2D6 weakly and CYP3A4 modestly, and may increase exposure to the active metabolite of fesoterodine. The expected change is small.
How serious is the interaction between Fesoterodine and Fluvoxamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; monitor for anticholinergic adverse effects.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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