Drug interactions
Fesoterodine + Iloperidone
Severity: Minor
Fesoterodine and Iloperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone has modest anticholinergic activity that may add to fesoterodine effects, producing dry mouth, constipation or urinary retention. Claims of reduced absorption and hypoglycemia are not supported. Iloperidone also prolongs the QT interval, but fesoterodine does not substantially add to this at usual doses.
What this interaction means in plain words
Fesoterodine and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Iloperidone belongs to Central Nervous System.
Why it happens
Weak additive antimuscarinic effects.
What to do
Monitor for anticholinergic adverse effects; no dose adjustment is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fesoterodine and Iloperidone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Fesoterodine
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Fesoterodine with Iloperidone?
MediHelp rates the interaction as minor. Fesoterodine and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iloperidone has modest anticholinergic activity that may add to fesoterodine effects, producing dry mouth, constipation or urinary retention. Claims of reduced absorption and hypoglycemia are not supported. Iloperidone also prolongs the QT interval, but fesoterodine does not substantially add to this at usual doses.
How serious is the interaction between Fesoterodine and Iloperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects; no dose adjustment is usually required.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
