Drug interactions
Fesoterodine + Ipratropium
Severity: Moderate
Fesoterodine and Ipratropium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fesoterodine is a systemic antimuscarinic, so ipratropium may add to dry mouth, constipation, urinary retention and blurred vision. The effect is generally mild given low systemic ipratropium exposure.
What this interaction means in plain words
Fesoterodine and Ipratropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fesoterodine belongs to Genitourinary; Ipratropium belongs to Respiratory.
Why it happens
Additive muscarinic receptor blockade.
What to do
Monitor for constipation, urinary retention and dry mouth. Consider dose reduction of fesoterodine if anticholinergic symptoms are bothersome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Fesoterodine
Frequently asked questions
Can I take Fesoterodine with Ipratropium?
MediHelp rates the interaction as moderate. Fesoterodine and Ipratropium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fesoterodine is a systemic antimuscarinic, so ipratropium may add to dry mouth, constipation, urinary retention and blurred vision. The effect is generally mild given low systemic ipratropium exposure.
How serious is the interaction between Fesoterodine and Ipratropium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for constipation, urinary retention and dry mouth. Consider dose reduction of fesoterodine if anticholinergic symptoms are bothersome.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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