Drug interactions
Finasteride + Fosamprenavir
Severity: Minor
Finasteride and Fosamprenavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fosamprenavir, converted to amprenavir, inhibits CYP3A4 and may raise finasteride concentrations. Clinically significant toxicity is unlikely given finasteride's tolerability.
What this interaction means in plain words
Finasteride and Fosamprenavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4-mediated finasteride metabolism.
What to do
No dose adjustment is required; monitor for finasteride adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Frequently asked questions
Can I take Finasteride with Fosamprenavir?
MediHelp rates the interaction as minor. Finasteride and Fosamprenavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fosamprenavir, converted to amprenavir, inhibits CYP3A4 and may raise finasteride concentrations. Clinically significant toxicity is unlikely given finasteride's tolerability.
How serious is the interaction between Finasteride and Fosamprenavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required; monitor for finasteride adverse effects.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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