Drug interactions
Finasteride + Quinupristin / dalfopristin
Severity: Minor
Finasteride and Quinupristin / dalfopristin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinupristin/dalfopristin inhibits CYP3A4 and could modestly raise finasteride exposure. Finasteride has a wide safety margin, so the practical consequence is expected to be small.
What this interaction means in plain words
Finasteride and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Inhibition of CYP3A4-mediated finasteride metabolism by quinupristin/dalfopristin.
What to do
No dose change is needed for finasteride. Be aware of possible increased finasteride adverse effects such as sexual dysfunction if they emerge during the antibiotic course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Frequently asked questions
Can I take Finasteride with Quinupristin / dalfopristin?
MediHelp rates the interaction as minor. Finasteride and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinupristin/dalfopristin inhibits CYP3A4 and could modestly raise finasteride exposure. Finasteride has a wide safety margin, so the practical consequence is expected to be small.
How serious is the interaction between Finasteride and Quinupristin / dalfopristin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed for finasteride. Be aware of possible increased finasteride adverse effects such as sexual dysfunction if they emerge during the antibiotic course.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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