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Drug interactions

Fish oil triglycerides + Vortioxetine

Severity: Minor

Fish oil triglycerides and Vortioxetine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Vortioxetine, like other serotonergic antidepressants, can impair platelet function, and omega-3 fatty acids may modestly prolong bleeding time. Together they could slightly increase bruising or bleeding risk, though clinical significance is generally small.

What this interaction means in plain words

Fish oil triglycerides and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive effects on platelet function: reduced platelet serotonin uptake by vortioxetine and antiplatelet activity of omega-3 fatty acids.

What to do

No routine change is needed; watch for bruising or bleeding, especially if other antithrombotics are also used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fish oil triglycerides with Vortioxetine?

MediHelp rates the interaction as minor. Fish oil triglycerides and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vortioxetine, like other serotonergic antidepressants, can impair platelet function, and omega-3 fatty acids may modestly prolong bleeding time. Together they could slightly increase bruising or bleeding risk, though clinical significance is generally small.

How serious is the interaction between Fish oil triglycerides and Vortioxetine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; watch for bruising or bleeding, especially if other antithrombotics are also used.

What other medicines interact with Vortioxetine?

MediHelp also lists interactions of Vortioxetine with, for example, Isocarboxazid, Linezolid, Methylene blue. The full list is on the Vortioxetine page.

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