Drug interactions
Flibanserin + Nifedipine
Severity: Moderate
Flibanserin and Nifedipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nifedipine is a CYP3A4 substrate and not a meaningful inhibitor. Both drugs can lower blood pressure, so additive hypotension and syncope are possible.
What this interaction means in plain words
Flibanserin and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Flibanserin belongs to Genitourinary; Nifedipine belongs to Cardiovascular.
Why it happens
Additive hypotensive effects.
What to do
Monitor blood pressure and counsel the patient about orthostatic symptoms. Avoid alcohol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Nifedipine
Frequently asked questions
Can I take Flibanserin with Nifedipine?
MediHelp rates the interaction as moderate. Flibanserin and Nifedipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nifedipine is a CYP3A4 substrate and not a meaningful inhibitor. Both drugs can lower blood pressure, so additive hypotension and syncope are possible.
How serious is the interaction between Flibanserin and Nifedipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and counsel the patient about orthostatic symptoms. Avoid alcohol.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
Full monographs, dosing and an interaction checker in the MediHelp app
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