Drug interactions
Fludrocortisone + Saxagliptin
Severity: Minor
Fludrocortisone and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fludrocortisone has some glucocorticoid activity that can raise blood glucose. This may slightly reduce the glycemic effect of saxagliptin.
What this interaction means in plain words
Fludrocortisone and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fludrocortisone belongs to Endocrine; Saxagliptin belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism, as corticosteroid glucocorticoid activity increases hepatic glucose output and insulin resistance.
What to do
Monitor blood glucose when fludrocortisone is started or changed, and adjust antidiabetic therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fludrocortisone
Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Frequently asked questions
Can I take Fludrocortisone with Saxagliptin?
MediHelp rates the interaction as minor. Fludrocortisone and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fludrocortisone has some glucocorticoid activity that can raise blood glucose. This may slightly reduce the glycemic effect of saxagliptin.
How serious is the interaction between Fludrocortisone and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when fludrocortisone is started or changed, and adjust antidiabetic therapy if control worsens.
What other medicines interact with Fludrocortisone?
MediHelp also lists interactions of Fludrocortisone with, for example, Mifepristone, Aldesleukin, Amphotericin b. The full list is on the Fludrocortisone page.
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