Drug interactions
Fluoxetine + Formoterol-mometasone
Severity: Moderate
Fluoxetine and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoxetine can prolong the QT interval, particularly at higher doses or with hypokalemia, and formoterol may add to this and lower potassium. The combined risk of arrhythmia is modest but relevant in patients with other risk factors.
What this interaction means in plain words
Fluoxetine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluoxetine belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia as an aggravating factor.
What to do
Check potassium and magnesium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs. Avoid high formoterol doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Fluoxetine
- Fluoxetine + Isocarboxazid Contraindicated
- Fluoxetine + Mavacamten Contraindicated
- Fluoxetine + Methylene blue Contraindicated
- Fluoxetine + Phenelzine Contraindicated
- Fluoxetine + Pimozide Contraindicated
- Fluoxetine + Rasagiline Contraindicated
Frequently asked questions
Can I take Fluoxetine with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Fluoxetine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fluoxetine can prolong the QT interval, particularly at higher doses or with hypokalemia, and formoterol may add to this and lower potassium. The combined risk of arrhythmia is modest but relevant in patients with other risk factors.
How serious is the interaction between Fluoxetine and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and consider an ECG in patients with cardiac disease or other QT-prolonging drugs. Avoid high formoterol doses.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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