Drug interactions
Flurbiprofen + Potassium iodide
Severity: Minor
Flurbiprofen and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs can reduce renal potassium excretion by suppressing renin and aldosterone. Hyperkalemia is possible, mainly with renal impairment or other potassium-raising drugs, though doses of potassium iodide are usually small.
What this interaction means in plain words
Flurbiprofen and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
NSAID-induced hyporeninemic hypoaldosteronism reduces potassium excretion, adding to the potassium load.
What to do
Monitor serum potassium in patients with renal impairment, diabetes or on other potassium-raising drugs; no action is usually needed otherwise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Flurbiprofen with Potassium iodide?
MediHelp rates the interaction as minor. Flurbiprofen and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs can reduce renal potassium excretion by suppressing renin and aldosterone. Hyperkalemia is possible, mainly with renal impairment or other potassium-raising drugs, though doses of potassium iodide are usually small.
How serious is the interaction between Flurbiprofen and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with renal impairment, diabetes or on other potassium-raising drugs; no action is usually needed otherwise.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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