Drug interactions
Flurbiprofen + Succinylcholine
Severity: Minor
Flurbiprofen and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Succinylcholine raises serum potassium and NSAIDs have only a minor potassium-raising tendency, so the clinical interaction is not meaningful for a single perioperative dose.
What this interaction means in plain words
Flurbiprofen and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Succinylcholine belongs to Musculoskeletal.
Why it happens
Succinylcholine causes potassium release from muscle; NSAIDs mildly reduce renal potassium excretion, an additive effect that is small.
What to do
No specific action is needed in most patients; check potassium in those with renal impairment or existing hyperkalemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Succinylcholine
Frequently asked questions
Can I take Flurbiprofen with Succinylcholine?
MediHelp rates the interaction as minor. Flurbiprofen and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Succinylcholine raises serum potassium and NSAIDs have only a minor potassium-raising tendency, so the clinical interaction is not meaningful for a single perioperative dose.
How serious is the interaction between Flurbiprofen and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed in most patients; check potassium in those with renal impairment or existing hyperkalemia.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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