Drug interactions
Fluticasone-vilanterol + Sertraline
Severity: Minor
Fluticasone-vilanterol and Sertraline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sertraline has a low potential to prolong the QT interval, and vilanterol adds adrenergic cardiac effects. The combination is unlikely to cause problems in most patients.
What this interaction means in plain words
Fluticasone-vilanterol and Sertraline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluticasone-vilanterol belongs to Respiratory; Sertraline belongs to Central Nervous System.
Why it happens
Possible small additive effects on cardiac repolarization; the interaction is largely theoretical.
What to do
No routine action; consider ECG and electrolyte checks in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluticasone-vilanterol
Other interactions of Sertraline
- Isocarboxazid + Sertraline Contraindicated
- Methylene blue + Sertraline Contraindicated
- Phenelzine + Sertraline Contraindicated
- Pimozide + Sertraline Contraindicated
- Selegiline transdermal + Sertraline Contraindicated
- Selegiline + Sertraline Contraindicated
Frequently asked questions
Can I take Fluticasone-vilanterol with Sertraline?
MediHelp rates the interaction as minor. Fluticasone-vilanterol and Sertraline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sertraline has a low potential to prolong the QT interval, and vilanterol adds adrenergic cardiac effects. The combination is unlikely to cause problems in most patients.
How serious is the interaction between Fluticasone-vilanterol and Sertraline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; consider ECG and electrolyte checks in patients with other QT risk factors.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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