Drug interactions
Fluvastatin + Lasmiditan
Severity: Minor
Fluvastatin and Lasmiditan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits BCRP in vitro, and fluvastatin is a BCRP substrate. Exposure to fluvastatin may increase, though the clinical significance is uncertain given the intermittent use of lasmiditan.
What this interaction means in plain words
Fluvastatin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvastatin belongs to Cardiovascular; Lasmiditan belongs to Central Nervous System.
Why it happens
Lasmiditan inhibits BCRP-mediated efflux of fluvastatin, based largely on in vitro data.
What to do
No routine change is needed with occasional lasmiditan doses. Advise the patient to report unexplained muscle symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvastatin
- Cyclosporin + Fluvastatin Major
- Fluvastatin + Gemfibrozil Major
- Fluvastatin + Letermovir Major
- Fluvastatin + Red yeast rice Major
- Apalutamide + Fluvastatin Moderate
- Cholestyramine + Fluvastatin Moderate
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Fluvastatin with Lasmiditan?
MediHelp rates the interaction as minor. Fluvastatin and Lasmiditan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits BCRP in vitro, and fluvastatin is a BCRP substrate. Exposure to fluvastatin may increase, though the clinical significance is uncertain given the intermittent use of lasmiditan.
How serious is the interaction between Fluvastatin and Lasmiditan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed with occasional lasmiditan doses. Advise the patient to report unexplained muscle symptoms.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporin, Gemfibrozil, Letermovir. The full list is on the Fluvastatin page.
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