Drug interactions
Fluvastatin + Mesterolone
Severity: Minor
Fluvastatin and Mesterolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The concern is extrapolated from danazol with CYP3A4-metabolized statins. Fluvastatin is mainly metabolized by CYP2C9 and mesterolone has no established effect on it.
What this interaction means in plain words
Fluvastatin and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvastatin belongs to Cardiovascular; Mesterolone belongs to Endocrine.
Why it happens
No established mechanism; additive myotoxicity is only theoretical.
What to do
No dose change is needed. Monitor for muscle pain or weakness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvastatin
- Cyclosporin + Fluvastatin Major
- Fluvastatin + Gemfibrozil Major
- Fluvastatin + Letermovir Major
- Fluvastatin + Red yeast rice Major
- Apalutamide + Fluvastatin Moderate
- Cholestyramine + Fluvastatin Moderate
Other interactions of Mesterolone
Frequently asked questions
Can I take Fluvastatin with Mesterolone?
MediHelp rates the interaction as minor. Fluvastatin and Mesterolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The concern is extrapolated from danazol with CYP3A4-metabolized statins. Fluvastatin is mainly metabolized by CYP2C9 and mesterolone has no established effect on it.
How serious is the interaction between Fluvastatin and Mesterolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor for muscle pain or weakness.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporin, Gemfibrozil, Letermovir. The full list is on the Fluvastatin page.
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