Drug interactions
Fondaparinux + Garlic
Severity: Minor
Fondaparinux and Garlic: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have mild antiplatelet activity and may add to the bleeding tendency of fondaparinux. Evidence is limited and the clinical effect is probably small.
What this interaction means in plain words
Fondaparinux and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fondaparinux belongs to Cardiovascular; Garlic belongs to Gastrointestinal Tract.
Why it happens
Possible additive effect from garlic-related platelet inhibition and fondaparinux factor Xa inhibition.
What to do
Advise avoiding concentrated garlic supplements while on fondaparinux. Monitor for bruising or bleeding if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Fondaparinux with Garlic?
MediHelp rates the interaction as minor. Fondaparinux and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have mild antiplatelet activity and may add to the bleeding tendency of fondaparinux. Evidence is limited and the clinical effect is probably small.
How serious is the interaction between Fondaparinux and Garlic?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding concentrated garlic supplements while on fondaparinux. Monitor for bruising or bleeding if used.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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