Drug interactions
Formoterol + Ozanimod
Severity: Moderate
Formoterol and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can slow heart rate and affect cardiac conduction, while formoterol can cause tachycardia and QT prolongation. Combined use may produce unpredictable effects on heart rhythm, particularly in patients with underlying cardiac disease.
What this interaction means in plain words
Formoterol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Ozanimod belongs to Central Nervous System.
Why it happens
Additive effects on cardiac rhythm and conduction: sphingosine-1-phosphate receptor modulation lowers heart rate while beta-2 agonism can prolong QT.
What to do
Obtain a baseline ECG before starting ozanimod and seek cardiology advice in patients taking QT-prolonging drugs. Monitor heart rate and rhythm, and keep potassium and magnesium normal.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Formoterol with Ozanimod?
MediHelp rates the interaction as moderate. Formoterol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod can slow heart rate and affect cardiac conduction, while formoterol can cause tachycardia and QT prolongation. Combined use may produce unpredictable effects on heart rhythm, particularly in patients with underlying cardiac disease.
How serious is the interaction between Formoterol and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG before starting ozanimod and seek cardiology advice in patients taking QT-prolonging drugs. Monitor heart rate and rhythm, and keep potassium and magnesium normal.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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