Drug interactions
Formoterol + Propylhexedrine
Severity: Moderate
Formoterol and Propylhexedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a sympathomimetic decongestant, and combined use with formoterol may add to increases in heart rate and blood pressure. Palpitations, tremor and arrhythmia are more likely in patients with heart disease.
What this interaction means in plain words
Formoterol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Propylhexedrine belongs to Respiratory.
Why it happens
Additive adrenergic stimulation from beta-2 agonism and sympathomimetic activity.
What to do
Monitor heart rate and blood pressure, and limit decongestant use to short courses at labeled doses. Avoid in patients with uncontrolled hypertension or arrhythmia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Formoterol with Propylhexedrine?
MediHelp rates the interaction as moderate. Formoterol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Propylhexedrine is a sympathomimetic decongestant, and combined use with formoterol may add to increases in heart rate and blood pressure. Palpitations, tremor and arrhythmia are more likely in patients with heart disease.
How serious is the interaction between Formoterol and Propylhexedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and limit decongestant use to short courses at labeled doses. Avoid in patients with uncontrolled hypertension or arrhythmia.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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