Drug interactions
Formoterol-mometasone + Fostemsavir
Severity: Moderate
Formoterol-mometasone and Fostemsavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol can prolong the QTc interval, and fostemsavir has caused QTc prolongation at supratherapeutic doses. Together they may add to the risk of QT-related arrhythmias, particularly with other risk factors.
What this interaction means in plain words
Formoterol-mometasone and Fostemsavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Fostemsavir belongs to Anti Virals.
Why it happens
Additive effects on cardiac repolarization.
What to do
Obtain a baseline ECG in patients with QT risk factors and monitor QTc and electrolytes during coadministration. Correct hypokalemia and hypomagnesemia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Fostemsavir?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Fostemsavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Formoterol can prolong the QTc interval, and fostemsavir has caused QTc prolongation at supratherapeutic doses. Together they may add to the risk of QT-related arrhythmias, particularly with other risk factors.
How serious is the interaction between Formoterol-mometasone and Fostemsavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with QT risk factors and monitor QTc and electrolytes during coadministration. Correct hypokalemia and hypomagnesemia.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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