Drug interactions
Formoterol-mometasone + Ibutilide
Severity: Major
Formoterol-mometasone and Ibutilide: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ibutilide carries a high, well-documented risk of torsades de pointes. Formoterol may add to QT prolongation and lower potassium, which further increases this risk.
What this interaction means in plain words
Formoterol-mometasone and Ibutilide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Formoterol-mometasone belongs to Respiratory; Ibutilide belongs to Cardiovascular.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia amplifying proarrhythmic risk.
What to do
Avoid giving formoterol around ibutilide administration where possible. If it is unavoidable, correct potassium and magnesium and keep continuous ECG monitoring during and after the ibutilide infusion.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Other interactions of Ibutilide
- Amiodarone + Ibutilide Contraindicated
- Amisulpride + Ibutilide Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Clarithromycin + Ibutilide Contraindicated
- Desipramine + Ibutilide Contraindicated
- Dolasetron + Ibutilide Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Ibutilide?
MediHelp rates the interaction as major. Formoterol-mometasone and Ibutilide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ibutilide carries a high, well-documented risk of torsades de pointes. Formoterol may add to QT prolongation and lower potassium, which further increases this risk.
How serious is the interaction between Formoterol-mometasone and Ibutilide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving formoterol around ibutilide administration where possible. If it is unavoidable, correct potassium and magnesium and keep continuous ECG monitoring during and after the ibutilide infusion.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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