Drug interactions
Formoterol-mometasone + Levofloxacin
Severity: Moderate
Formoterol-mometasone and Levofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levofloxacin and formoterol can each prolong the QT interval, and formoterol-induced hypokalemia heightens the risk of torsades de pointes. Fluoroquinolones given with corticosteroids also increase the risk of tendinopathy, although inhaled mometasone exposure is low.
What this interaction means in plain words
Formoterol-mometasone and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Levofloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation and hypokalemia, plus possible additive tendon toxicity with corticosteroids.
What to do
Check ECG and correct potassium and magnesium in patients with QT risk factors. Advise patients to stop levofloxacin and seek advice if tendon pain occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Levofloxacin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Frequently asked questions
Can I take Formoterol-mometasone with Levofloxacin?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levofloxacin and formoterol can each prolong the QT interval, and formoterol-induced hypokalemia heightens the risk of torsades de pointes. Fluoroquinolones given with corticosteroids also increase the risk of tendinopathy, although inhaled mometasone exposure is low.
How serious is the interaction between Formoterol-mometasone and Levofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and correct potassium and magnesium in patients with QT risk factors. Advise patients to stop levofloxacin and seek advice if tendon pain occurs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
