Drug interactions
Formoterol-mometasone + Nebivolol
Severity: Moderate
Formoterol-mometasone and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol is a highly beta1-selective blocker, but at higher doses it can lose selectivity and blunt the effect of formoterol, with a risk of bronchospasm in susceptible patients. The risk is lower than with nonselective agents.
What this interaction means in plain words
Formoterol-mometasone and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Nebivolol belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism at beta-adrenoceptors, with selectivity lost at higher nebivolol doses.
What to do
Use the lowest effective nebivolol dose and monitor respiratory symptoms and peak flow. Review the need for the beta-blocker in patients with poorly controlled asthma.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Formoterol-mometasone with Nebivolol?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nebivolol is a highly beta1-selective blocker, but at higher doses it can lose selectivity and blunt the effect of formoterol, with a risk of bronchospasm in susceptible patients. The risk is lower than with nonselective agents.
How serious is the interaction between Formoterol-mometasone and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective nebivolol dose and monitor respiratory symptoms and peak flow. Review the need for the beta-blocker in patients with poorly controlled asthma.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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