Drug interactions
Formoterol-mometasone + Procarbazine
Severity: Moderate
Formoterol-mometasone and Procarbazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Procarbazine has monoamine oxidase inhibiting properties, and MAO inhibitors can potentiate cardiovascular effects of sympathomimetic drugs. Formoterol labeling advises caution with MAO inhibitors because of possible arrhythmia and hypertensive responses.
What this interaction means in plain words
Formoterol-mometasone and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Procarbazine belongs to Oncology.
Why it happens
MAO inhibition may enhance adrenergic effects of beta-2 agonists on the cardiovascular system.
What to do
Monitor heart rate, blood pressure and ECG symptoms when formoterol is used during procarbazine therapy. Reduce formoterol use if tachycardia or hypertension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Procarbazine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine has monoamine oxidase inhibiting properties, and MAO inhibitors can potentiate cardiovascular effects of sympathomimetic drugs. Formoterol labeling advises caution with MAO inhibitors because of possible arrhythmia and hypertensive responses.
How serious is the interaction between Formoterol-mometasone and Procarbazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG symptoms when formoterol is used during procarbazine therapy. Reduce formoterol use if tachycardia or hypertension develops.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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