Drug interactions
Fosaprepitant + Galantamine
Severity: Minor
Fosaprepitant and Galantamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aprepitant, the active form of fosaprepitant, is a moderate CYP3A4 inhibitor, but a single-dose regimen has a short and limited effect. Galantamine exposure might rise slightly, with little expected clinical consequence.
What this interaction means in plain words
Fosaprepitant and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fosaprepitant belongs to Gastrointestinal Tract; Galantamine belongs to Central Nervous System.
Why it happens
Transient CYP3A4 inhibition by aprepitant reduces galantamine metabolism.
What to do
No dose change is needed; monitor for nausea, bradycardia or dizziness around the time of chemotherapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Other interactions of Fosaprepitant
- Flibanserin + Fosaprepitant Contraindicated
- Fosaprepitant + Pimozide Contraindicated
- Alprazolam + Fosaprepitant Moderate
- Amiodarone + Fosaprepitant Moderate
- Amobarbital + Fosaprepitant Moderate
- Apalutamide + Fosaprepitant Moderate
Frequently asked questions
Can I take Fosaprepitant with Galantamine?
MediHelp rates the interaction as minor. Fosaprepitant and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aprepitant, the active form of fosaprepitant, is a moderate CYP3A4 inhibitor, but a single-dose regimen has a short and limited effect. Galantamine exposure might rise slightly, with little expected clinical consequence.
How serious is the interaction between Fosaprepitant and Galantamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor for nausea, bradycardia or dizziness around the time of chemotherapy.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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