Drug interactions
Furosemide + Propranolol
Severity: Minor
Furosemide and Propranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Furosemide and propranolol can be given together with additive blood pressure reduction. Potassium effects are small and not clearly significant, with furosemide-induced hypokalemia being the main concern. Furosemide has also been reported to modestly raise propranolol levels, which is rarely important.
What this interaction means in plain words
Furosemide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Furosemide belongs to Cardiovascular; Propranolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamics; loop diuretic potassium loss with minor beta-blocker effects on potassium distribution.
What to do
Monitor blood pressure, heart rate and serum potassium during initiation and dose changes. Correct hypokalemia as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
- Arformoterol + Propranolol Major
Frequently asked questions
Can I take Furosemide with Propranolol?
MediHelp rates the interaction as minor. Furosemide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Furosemide and propranolol can be given together with additive blood pressure reduction. Potassium effects are small and not clearly significant, with furosemide-induced hypokalemia being the main concern. Furosemide has also been reported to modestly raise propranolol levels, which is rarely important.
How serious is the interaction between Furosemide and Propranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium during initiation and dose changes. Correct hypokalemia as needed.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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