Drug interactions
Galantamine + Letermovir
Severity: Minor
Galantamine and Letermovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Letermovir inhibits CYP3A4 and may modestly raise galantamine exposure. This could increase cholinergic adverse effects such as nausea, vomiting and bradycardia.
What this interaction means in plain words
Galantamine and Letermovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Galantamine belongs to Central Nervous System; Letermovir belongs to Anti Virals.
Why it happens
Inhibition of CYP3A4-mediated galantamine metabolism by letermovir.
What to do
Monitor for nausea, vomiting and bradycardia during co-therapy. Reduce the galantamine dose if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Other interactions of Letermovir
- Ergotamine + Letermovir Contraindicated
- Letermovir + Pimozide Contraindicated
- Apalutamide + Letermovir Major
- Atorvastatin + Letermovir Major
- Carbamazepine + Letermovir Major
- Colchicine + Letermovir Major
Frequently asked questions
Can I take Galantamine with Letermovir?
MediHelp rates the interaction as minor. Galantamine and Letermovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Letermovir inhibits CYP3A4 and may modestly raise galantamine exposure. This could increase cholinergic adverse effects such as nausea, vomiting and bradycardia.
How serious is the interaction between Galantamine and Letermovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for nausea, vomiting and bradycardia during co-therapy. Reduce the galantamine dose if they occur.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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