Drug interactions
Galantamine + Tipranavir
Severity: Minor
Galantamine and Tipranavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tipranavir, usually given with ritonavir, may raise galantamine levels through inhibition of its metabolism. Any increase is likely to be modest, but cholinergic adverse effects could become more frequent.
What this interaction means in plain words
Galantamine and Tipranavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Galantamine belongs to Central Nervous System; Tipranavir belongs to Anti Virals.
Why it happens
Tipranavir/ritonavir may inhibit CYP2D6 and CYP3A4, though tipranavir itself also has inducing effects, so the net effect is uncertain.
What to do
Monitor for bradycardia, gastrointestinal upset and dizziness when starting the combination, and reduce the galantamine dose if these occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Other interactions of Tipranavir
- Alfuzosin + Tipranavir Contraindicated
- Amiodarone + Tipranavir Contraindicated
- Atorvastatin + Tipranavir Contraindicated
- Avanafil + Tipranavir Contraindicated
- Cisapride + Tipranavir Contraindicated
- Colchicine + Tipranavir Contraindicated
Frequently asked questions
Can I take Galantamine with Tipranavir?
MediHelp rates the interaction as minor. Galantamine and Tipranavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tipranavir, usually given with ritonavir, may raise galantamine levels through inhibition of its metabolism. Any increase is likely to be modest, but cholinergic adverse effects could become more frequent.
How serious is the interaction between Galantamine and Tipranavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bradycardia, gastrointestinal upset and dizziness when starting the combination, and reduce the galantamine dose if these occur.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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